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nrf2 antagonist ml385  (MedChemExpress)


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    MedChemExpress nrf2 antagonist ml385
    Nrf2 Antagonist Ml385, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 96/100, based on 679 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/nrf2 antagonist ml385/product/MedChemExpress
    Average 96 stars, based on 679 article reviews
    nrf2 antagonist ml385 - by Bioz Stars, 2026-02
    96/100 stars

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    nrf2 antagonist  (MedChemExpress)
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    MedChemExpress nrf2 antagonist
    <t>Nrf2</t> ( A ), HO-1 ( B ), p-iκb ( C ), p-p65 ( D ) protein level in bursa at P42. The results of each group were expressed as the mean ± standard error. Differences between seven light treatment groups were evaluated by one-way ANOVA, and values with no common letters differ significantly ( p < 0.05).
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    Nrf2 ( A ), HO-1 ( B ), p-iκb ( C ), p-p65 ( D ) protein level in bursa at P42. The results of each group were expressed as the mean ± standard error. Differences between seven light treatment groups were evaluated by one-way ANOVA, and values with no common letters differ significantly ( p < 0.05).

    Journal: Antioxidants

    Article Title: Melatonin Nuclear Receptors Mediate Green-and-Blue-Monochromatic-Light-Combinations-Inhibited B Lymphocyte Apoptosis in the Bursa of Chickens via Reducing Oxidative Stress and Nfκb Expression

    doi: 10.3390/antiox11040748

    Figure Lengend Snippet: Nrf2 ( A ), HO-1 ( B ), p-iκb ( C ), p-p65 ( D ) protein level in bursa at P42. The results of each group were expressed as the mean ± standard error. Differences between seven light treatment groups were evaluated by one-way ANOVA, and values with no common letters differ significantly ( p < 0.05).

    Article Snippet: In addition, bursal B lymphocytes of the G→B group were prepared with either RORα antagonist (SR3335, 5 μM, MCE, Weehawken, NJ, USA), RORα agonist (SR1078, 10 μM, MCE, Weehawken, NJ, USA), RORγ antagonist (GSK2981278, 1 μM, MCE, Weehawken, NJ, USA), Nrf2 antagonist (ML385, 5 μM, MCE, Weehawken, NJ, USA), Nfκb antagonist (BAY, 1 μM, MCE, Weehawken, NJ, USA) for 30 min before the addition of LPS and melatonin.

    Techniques:

    Effects of RORα antagonists, RORα agonist, RORγ antagonist, Nrf2 antagonists and p65 antagonists on Caspase-3 protein ( A , B ), Bcl-2 protein ( C ), Bax protein ( D ), ROS level ( E ) of bursal B-lymphocyte in response to LPS in the G→B group. SR3335 is a RORα antagonist; SR1078 is a RORα agonist; GSK1981278 is a RORγ antagonist; ML385 is an NRF2 antagonist; BAY is a p65 antagonist. Differences between seven light treatment groups were evaluated by one-way ANOVA, and values with no common letters differ significantly ( p < 0.05).

    Journal: Antioxidants

    Article Title: Melatonin Nuclear Receptors Mediate Green-and-Blue-Monochromatic-Light-Combinations-Inhibited B Lymphocyte Apoptosis in the Bursa of Chickens via Reducing Oxidative Stress and Nfκb Expression

    doi: 10.3390/antiox11040748

    Figure Lengend Snippet: Effects of RORα antagonists, RORα agonist, RORγ antagonist, Nrf2 antagonists and p65 antagonists on Caspase-3 protein ( A , B ), Bcl-2 protein ( C ), Bax protein ( D ), ROS level ( E ) of bursal B-lymphocyte in response to LPS in the G→B group. SR3335 is a RORα antagonist; SR1078 is a RORα agonist; GSK1981278 is a RORγ antagonist; ML385 is an NRF2 antagonist; BAY is a p65 antagonist. Differences between seven light treatment groups were evaluated by one-way ANOVA, and values with no common letters differ significantly ( p < 0.05).

    Article Snippet: In addition, bursal B lymphocytes of the G→B group were prepared with either RORα antagonist (SR3335, 5 μM, MCE, Weehawken, NJ, USA), RORα agonist (SR1078, 10 μM, MCE, Weehawken, NJ, USA), RORγ antagonist (GSK2981278, 1 μM, MCE, Weehawken, NJ, USA), Nrf2 antagonist (ML385, 5 μM, MCE, Weehawken, NJ, USA), Nfκb antagonist (BAY, 1 μM, MCE, Weehawken, NJ, USA) for 30 min before the addition of LPS and melatonin.

    Techniques:

    Effects of RORα antagonists, RORα agonist, RORγ antagonist, Nrf2 antagonists and p65 antagonists on Nrf2 ( A ), HO-1 ( B ), p-iκb ( C ), p-p65 ( D ) protein level of bursal B-lymphocyte in response to LPS in the G→B group. SR3335 is a RORα antagonist; SR1078 is a RORα agonist; GSK1981278 is a RORγ antagonist; ML385 is an NRF2 antagonist; BAY is a p65 antagonist. Differences between seven light treatment groups were evaluated by one-way ANOVA, and values with no common letters differ significantly ( p < 0.05).

    Journal: Antioxidants

    Article Title: Melatonin Nuclear Receptors Mediate Green-and-Blue-Monochromatic-Light-Combinations-Inhibited B Lymphocyte Apoptosis in the Bursa of Chickens via Reducing Oxidative Stress and Nfκb Expression

    doi: 10.3390/antiox11040748

    Figure Lengend Snippet: Effects of RORα antagonists, RORα agonist, RORγ antagonist, Nrf2 antagonists and p65 antagonists on Nrf2 ( A ), HO-1 ( B ), p-iκb ( C ), p-p65 ( D ) protein level of bursal B-lymphocyte in response to LPS in the G→B group. SR3335 is a RORα antagonist; SR1078 is a RORα agonist; GSK1981278 is a RORγ antagonist; ML385 is an NRF2 antagonist; BAY is a p65 antagonist. Differences between seven light treatment groups were evaluated by one-way ANOVA, and values with no common letters differ significantly ( p < 0.05).

    Article Snippet: In addition, bursal B lymphocytes of the G→B group were prepared with either RORα antagonist (SR3335, 5 μM, MCE, Weehawken, NJ, USA), RORα agonist (SR1078, 10 μM, MCE, Weehawken, NJ, USA), RORγ antagonist (GSK2981278, 1 μM, MCE, Weehawken, NJ, USA), Nrf2 antagonist (ML385, 5 μM, MCE, Weehawken, NJ, USA), Nfκb antagonist (BAY, 1 μM, MCE, Weehawken, NJ, USA) for 30 min before the addition of LPS and melatonin.

    Techniques:

    Effects of RORα antagonists, RORα agonist, RORγ antagonist, Nrf2 antagonists and p65 antagonists on pro-inflammatory cytokine TNF-α ( A ), IFN-γ ( B ), IL-6 ( C ), anti-inflammatory cytokine IL-10 ( D ) level of bursal B-lymphocyte in response to LPS in the G→B group. SR3335 is a RORα antagonist; SR1078 is a RORα agonist; GSK1981278 is a RORγ antagonist; ML385 is an NRF2 antagonist; BAY is a p65 antagonist. Differences between seven light treatment groups were evaluated by one-way ANOVA, and values with no common letters differ significantly ( p < 0.05).

    Journal: Antioxidants

    Article Title: Melatonin Nuclear Receptors Mediate Green-and-Blue-Monochromatic-Light-Combinations-Inhibited B Lymphocyte Apoptosis in the Bursa of Chickens via Reducing Oxidative Stress and Nfκb Expression

    doi: 10.3390/antiox11040748

    Figure Lengend Snippet: Effects of RORα antagonists, RORα agonist, RORγ antagonist, Nrf2 antagonists and p65 antagonists on pro-inflammatory cytokine TNF-α ( A ), IFN-γ ( B ), IL-6 ( C ), anti-inflammatory cytokine IL-10 ( D ) level of bursal B-lymphocyte in response to LPS in the G→B group. SR3335 is a RORα antagonist; SR1078 is a RORα agonist; GSK1981278 is a RORγ antagonist; ML385 is an NRF2 antagonist; BAY is a p65 antagonist. Differences between seven light treatment groups were evaluated by one-way ANOVA, and values with no common letters differ significantly ( p < 0.05).

    Article Snippet: In addition, bursal B lymphocytes of the G→B group were prepared with either RORα antagonist (SR3335, 5 μM, MCE, Weehawken, NJ, USA), RORα agonist (SR1078, 10 μM, MCE, Weehawken, NJ, USA), RORγ antagonist (GSK2981278, 1 μM, MCE, Weehawken, NJ, USA), Nrf2 antagonist (ML385, 5 μM, MCE, Weehawken, NJ, USA), Nfκb antagonist (BAY, 1 μM, MCE, Weehawken, NJ, USA) for 30 min before the addition of LPS and melatonin.

    Techniques: